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Cholestasis: symptoms and effective treatment

Cholestasis is characterized by the fact that the body decreases the level of bile and causes are liver problems.

It is possible to divide the disease into several of the most common forms:

1. Intrahepatic form can be expressed:

  • functional cholestasis;
  • as morfologicheskie cholestasis;
  • as clinical cholestasis.

2. Extrahepatic form develops in the bile ducts.

The causes of cholestasis

The cholestasis may be several reasons, but the main is always damage of liver cells bile acid. And this in turn is caused by:

  • External factors. Is the influence of alcohol, viral liver disease, toxic damage, overdose and complications from taking drugs;
  • Chronic diseases. Tuberculosis, cirrhosis, sarkoidoz;
  • Various diseases that affect the liver.

Symptoms of cholestasis

All the symptoms that are observed in a patient with cholestasis can be explained in the following points:

  • Bile starts in a large volume to flow into the blood;
  • In the intestine, the amount of bile is nearly or completely absent;
  • Gall effect on liver cells.

Perovymi symptoms can be itching of the liver, as well as beginning disorders in the digestion of food.

It is possible, in some cases, to observe the change in pigmentation of the skin. Changes in mood, and fatigue, can be symptoms.

Oven patient begins to grow in size, in principle without cirrhosis, enlarged liver during cholestasis is extremely rare.

To the primary symptom is the discoloration of the stool, and steatorrhea, in which defecation is allocated the excess fat.

Night blindness, another symptom, is directly dependent on the development of cholestasis, this is due to the drop in the body's level of vitamin K.

Cholestasis, in violation of absorbability affects calcium levels, which leads to changes in bone tissue.

Disturbed digestion, and diarrhea removes too much fluid from the body, whereby, it is possible to observe a decrease in weight of the patient.

The skin can start to act as a tumor-like spots, they are a consequence of disorders of lipid metabolism in the body and are localized on the face, neck, back. Read more about lipoma can be found In the treatment of cholestasis, the most effective method is etiotropic therapy. This means that the treatmentwill be quite specific, and will be aimed primarily at the elimination of causes of cholestasis.

Some studies demonstrate the effectiveness of ursodeoxycholic acid, and it is effective and cirrhosis of the liver caused by alcohol poisoning.

Plasmapheresis and antagonists of opioids designed to cope with pruritus.

During the treatment of cholestasis observe of a diet low in fat. In addition, assigned to vitamins C,D,and E. be Sure to take girorastvorimie drugs.

In the case of mechanical obstruction in the bile duct blockage of the biliary tract, surgical intervention is necessary, which may be a conventional or endoscopic.