Mastocytosis: treatment, photo

Mastocitos called massive education in special blood cells called mast. This is a disease that refers to diseases of the blood system. Together with the mast are formed in the blood and tissue basophils and lubricity. Cells after obrazovaniya begin to impregnate him not only the skin, but many internal organs.

The causes of the disease

Today it is accepted to distinguish two forms of the disease, is a skin and system. In order to start treatment, you must know that the cutaneous form affects the child, and no matter whether it is a boy or a girl.

Most often the disease is diagnosed in children up to 2 years. However, most children mastocytosis completely disappears in adolescence.

But the second form of the disease – systemic mastocytosis affects the patient is already an adult. In this case, the disease runs hard and has no tendency to heal itself.

In medicine so far there is no established opinion about the exact cause of the disease. One of the most common theories attempting to explain the occurrence of mastocytosis defeat a certain number of chromosomes, which are then transmitted via a hereditary route.

Important! However, more than half of all patients do not have a family history of mastocytosis with relatives.

Forms of mastocytosis

Mastocytosis can be divided into several forms based on the development and course of the disease, age of its appearance and clinical manifestations:

• Infant. As the name implies, this form is characteristic of children up to 2 years. This form is extremely rare transformirovalsya in systemic disease, and over time generally samoistselyatsya.
• Single or Solitary mastocytoma. In this sense, mastocytoma may be submitted by the formation of lesions that are limited to a few areas.
• The cutaneous form. The disease in this form can often hit the patient is in adolescence or adulthood. The symptoms of lesion is more pronounced and much more often. However, this form of the disease as well as the previous one, not prone to progression. Cutaneous in rare cases can be transformed into the system and then there is the process and internal organ involvement.
• System form. This type always takes place osoznanno and with the defeat of the internal organs.

Important! The latter form of mastocytosis, a malignant type which occurs in the form tuckaleechee leukemia. This form is characterized by extremely rapid development and poor prognosis.

Diagnosis of the disease

In the diagnosis of mastocytosis are the clinical manifestations of the disease and detection in tissues and in the skin of a large number of fat cells.

Conducted biochemical research blood, which focuses on shifts formula. In addition, it is important to monitor the amount of fat cells and the amount of waste products.

In addition to blood tests, the diagnosis of mastocytosis is

If the mastocytosis violates the work of internal organs, diagnosis involves the use of ultrasound or CT. This is especially true of internal organs such as the liver or spleen, which are extremely sensitive to the mastocytosis.

Treatment of mastocytosis

Treatment of disease can be attributed to the sections of Hematology and therapy, and that experts in these areas and provide treatment. Unfortunately, specific treatment of mastocytosis so still not developed, and the whole treatment relates only to symptomatic treatment.

In symptomatic therapy based on the elimination or reduction of the production of biologically active substances in which take part the fat cells.

Note the main medications used in the treatment of:

• Antihistamines. Suprastin, tavegil, side effects of the drug and analogues.
• Stabilisers membranes fat cells, here are the most common drugs is — nedocromil sodium, ketotifen.
• The use of alpha-interferon, despite the positive data in the laboratory, is still unrealistic. The drug is still being tested.
• Methylprednisolone and cyclosporine in high doses.

However, it should be said that while all of these drugs do not give effective results in the treatment of mastocytosis.

When systemic mastocytosis complicated by the recommended radical treatment, which is complete removal of the spleen.

And finally let us say that the prognosis in mastocytosis depends on the form of the disease and the degree of internal organ involvement, which already exists at the time of initiation of therapy.

Cutaneous mastocytosis, the prognosis is always favorable, with the systemic form prognosis may be unfavorable, when tuckaleechee leukemia the prognosis is almost always unfavorable.